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CORE BOLIC™ V2 is specifically crafted to boost energy levels, improve endurance, and accelerate muscle repair, making it an essential addition to your training regimen.\u003c\/p\u003e\n    \n    \u003cdiv\u003e\n        \u003cp\u003e\u003cb\u003eEach serving of CORE BOLIC™ V2 provides a powerful combination of key nutrients, including potent amino acids, essential vitamins, and advanced performance enhancers.\u003c\/b\u003e The formula features a premium blend of branched-chain amino acids (BCAAs) and other muscle-supporting compounds that help reduce muscle breakdown, promote lean muscle growth, and support faster recovery. This comprehensive approach ensures that you can push your limits during workouts and achieve your fitness goals more effectively.\u003c\/p\u003e\n        \u003cp\u003e\u003ci\u003eIt is designed with purity and efficacy in mind.\u003c\/i\u003e It is free from artificial colors, flavors, and preservatives, aligning with a clean and health-conscious lifestyle. 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DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex steroids such as testosterone and estrogen, up-regulating (increasing) immune response and countering the immunosuppressive actions of corticosteroids, and maybe the most impressive, directly and strongly suppressing the release of cortisol itself!\u003c\/p\u003e\n\u003cp\u003eThough DHEA’s properties have been well-established and understood for decades, derivatives and metabolites of DHEA have more recently been the subject of research in animals and humans – demonstrating effects that are, at times, many orders of magnitude more significant than the parent compound (up to 100x as potent!).\u003c\/p\u003e\n\u003cp\u003eLike DHEA, cortisol is one of the body’s most abundant and important endogenous steroids. While detailing in full the expansive list of cortisol’s functions is impossible, we can generally say that cortisol’s role in the human body is to break down bodily tissue and nutrients for the purpose of energy provision (to be catabolic), to act as an immunosuppressive, and to regulate blood sugar. Cortisol fulfills these functions by inducing gluconeogenesis (the breakdown of non-glucose intermediates, such as amino acids in muscle tissue, into glucose) and glycogenolysis (the breakdown of glycogen into glucose), inhibiting peripheral glucose utilization, and inhibiting cell lines critical to the body’s immune response.\u003c\/p\u003e\n\u003cp\u003eIn less complex terms, we can simply say that cortisol is responsible for inhibiting many of the processes that we as fitness enthusiasts want to start, and for starting many of the processes that we want to inhibit. Cortisol plays a role in:\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e1.\u003c\/b\u003e Preventing our muscle cells from uptaking glucose (inducing insulin resistance).\u003cbr\u003e\u003cb\u003e2.\u003c\/b\u003e Preventing muscle protein synthesis.\u003cbr\u003e\u003cb\u003e3.\u003c\/b\u003e The breakdown of glycogen (the compound responsible for that “full look”).\u003cbr\u003e\u003cb\u003e4.\u003c\/b\u003e Suppressing the immune processes involved in muscle growth.\u003c\/p\u003e\n\u003cp\u003eWhile these are necessary functions, their overexpression is precisely the opposite of what we want – in fact, certain trials in humans have shown that an increase in plasma cortisol within the physiologic range increases proteolysis (breakdown of proteins) and degrades whole body amino acid synthesis! That is bad, bad news.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eEnter DHEA and its metabolite, androstenetriol:\u003c\/b\u003e In emerging animal literature, both androstenetriol and its metabolites have been shown to possess very potent anti-glucocorticoid activity – remembering that cortisol is the parent compound for this group – and anti-immunosuppressive actions in a number of different tissue types. 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A modern weight loss solution using trademarked and patented ingredients, BURN addresses every major metabolic pathway of adipose creation and deposition. Whereas many thermogenics focus exclusively on stimulation, BURN contains ingredients with specific, high-quality evidence demonstrating their efficacy. SaffSerene™, for example, has been demonstrated to significantly reduce subjective feelings of hunger – one of the only dietary ingredients on the market that the FDA allows to make such a claim. KSM-66®, a patented extract of Ashwagandha, has been shown to significantly reduce cortisol – the body’s key stress hormone – in clinical trials. Together with the other premium ingredients in BURN, these two ingredients create an unparalleled weight management product.\u003c\/p\u003e\n\u003cp\u003eA complete formula, BURN is simply the modern evolution in weight loss supplements. 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Among the B-complex’s many critical roles are energy (protein, carbohydrates, and fat) metabolism, supporting and maintaining the healthy function of the adrenal glands, skeletal muscle function, and digestion.\u003c\/p\u003e\n\u003cp\u003eWhile rates of metabolism and clearance differ between each B vitamin, all B vitamins are water-soluble and are thus not stored in fat. As a result, the body simply excretes excess B vitamins in the urine and requires replenishment (from food or supplements) in order to maintain the cell functions to which B vitamins contribute. Along with choline and inositol added, collectively this group of nutrients are essential for maintaining normal energy levels, cognition, mood, bodily function, and well-being.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eB Vitamins (Thiamine, Riboflavin, Niacin, B6 [Pyridoxine], Folic Acid, B12, Biotin, and Pantothenic acid)\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eB vitamins are a group of eight essential vitamins with several critical functions in the body. Though both molecularly and physiologically distinct, they are also deeply interrelated in their effects, synthesis, and metabolism. Among the B-complex’s many critical roles are energy (protein, carbohydrates, and fat) metabolism, supporting and maintaining the healthy function of the adrenal glands, skeletal muscle function, and digestion.\u003c\/p\u003e\n\u003cp\u003eWhile rates of metabolism and clearance differ between each B vitamin, all B vitamins are water-soluble and are thus not stored in fat. As a result, the body simply excretes excess B vitamins in the urine and requires replenishment (from food or supplements) in order to maintain the cell functions to which B vitamins contribute. Collectively this group of vitamins are essential for maintaining normal cognition, mood, bodily function, and well-being.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCholine\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eCholine is an essential nutrient involved in numerous metabolic pathways, including DNA regulation and repair, protein function, and metabolism. Perhaps most importantly, the critical neurotransmitter acetylcholine is produced directly from free choline via cholinergic neurons. Acetylcholine is then responsible for a number of functions itself, most crucially as the compound which induces muscular contraction, and as the neuromodulator partially responsible for modulating risk\/reward, arousal, and enhancing memory.\u003c\/p\u003e\n\u003cp\u003eCholine’s essential role as a substrate for acetylcholine, and therefore brain development, is well documented in animal models. These studies demonstrate that levels of free maternal choline have a direct and fundamental impact on prenatal brain development, with the enhancements or deficits lasting into adulthood. Choline’s enhancing effect is particularly prominent in the hippocampus. In humans, the hippocampus is primarily involved in the consolidation of memory (taking short, episodic memory and translating it into long-term memory) and the learning of new information. Acetylcholine is a critical component in these processes, as mentioned above, and choline may therefore play a potential role in these processes as well by providing the substrate for acetylcholine synthesis.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eInositol\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eThe nutrient inositol, also known as myo-inositol, was once called “vitamin B8,” however, it was later found to be produced by humans, and thus is not technically a vitamin. Inositol heightens the activity of serotonin in the brain, and thus has a vital role in mood and emotional balance. Inositol is also a type of sugar that influences the insulin response and several hormones associated with mood and cognition. It has antioxidant properties that fight the damaging effects of free radicals in the brain, circulatory system, and other body tissues.\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":49911411933485,"sku":"210000013332","price":24.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0678\/5512\/2733\/files\/q9opxazepgln9qm1opm2.png?v=1759500144"},{"product_id":"core-commodities-acetyl-l-carnitine","title":"Core Nutritionals Acetyl L-Carnitine","description":"\u003cp\u003eAcetyl-L-Carnitine (ALCAR) is a little bit like your 401K: you need it, you know you should pay attention to it, but it’s not exactly the sexiest topic. We know; we feel you! But we also know that ALCAR is one of the most fascinating, useful, and physiologically exciting workout supplements on the planet. You’re hard-pressed to find a single other ingredient that is involved in so many critical bodily processes: fatty acid and carbohydrate metabolism, neurotransmission, exercise performance and capacity, brain function – the list goes on! So, like your 401K contribution, don’t forget to pay into your ALCAR fund.\u003c\/p\u003e\n\u003cp\u003eL-carnitine is a derivative of the amino acid lysine and, as certain conditions outpace the body’s ability to produce it, l-carnitine is considered a conditionally essential amino acid. While endogenous biosynthesis of l-carnitine from the amino acids lysine and methionine is sufficient for essential processes – along with dietary sources of carnitine from protein-rich red meat, for example – dietary supplementation of carnitine may pose benefits in certain physiological conditions. \u003c\/p\u003e\n\u003cp\u003eUnfortunately, due to excess metabolism of l-carnitine by microorganisms in the small intestine, exogenous supplementation with oral l-carnitine has proved ineffective. ALCAR, an acetylated version of l-carnitine, has considerably higher oral bioavailability, due likely to only partial hydrolytic metabolism. Once in the bloodstream, ALCAR plays a fundamental role in the production of energy, acting as the catalyst for the beta-oxidation of long chain fatty acids by the mitochondria; regulating the CoA to Acyl-CoA ratio (necessary for the production of ATP); and the metabolism of carbohydrates. 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That’s all great, and while we agree that whole food sources are the best, we also know that supplemental BCAAs can play a huge role in attaining your fitness goals. During a workout, before, or after, our 2:1:1 BCAAs are perfect for crafting a workout cocktail that is specific to you and your needs.\u003c\/p\u003e\n\n\u003cp\u003e\u003cb\u003eScience\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eBranched-Chain Amino Acids (BCAAs) have been demonstrated to possess a wide range of physiological benefits, including cell signaling, regulation of protein synthesis and cell metabolism, hypertrophic growth, and the mitigation or reduction of post-exercise muscle soreness. BCAAs themselves are considered essential amino acids, or EAAs, as the human body is not capable of synthesizing them. 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